Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 1.00 |
| ▸ | HTT | P42858 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4357272 | 1.00 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL8690719 | 0.86 | ALDH1A1 (0.76) | ALDH1A1SMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL29071609 | 0.86 | ALDH1A1 (0.77) | ALDH1A1SMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL8685573 | 0.83 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL28467331 | 0.82 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL6802019 | 0.82 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL28527982 | 0.82 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL6705979 | 0.82 | SMN1; SMN2 (0.72) | ALDH1A1SMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL30487282 | 0.82 | SMN1; SMN2 (0.72) | ALDH1A1SMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL8813099 | 0.82 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2HTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535386-B | Cyanoethylene sulfonyl anilide compound and preparation method and medical application thereof | 西南大学 | 2025-05-27 | — | — | CN | disclosed |
| CN-116535386-A | Cyanoethylene sulfonyl anilide compound and preparation method and medical application thereof | 西南大学 | 2023-08-04 | — | — | CN | disclosed |