Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30074420 | 0.91 | MEN1 (0.59) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL28524761 | 0.83 | NPC1 (0.54) | KMT2APOLBMAPTALDH1A1HPGD | |
| SCHEMBL2056400 | 0.81 | SPHK1 (0.53) | KMT2APOLBNPC1RAB9AHTT | |
| SCHEMBL8238318 | 0.81 | KIF11 (0.51) | POLBALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL28521165 | 0.78 | NPC1 (0.56) | MAPTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL28511551 | 0.78 | MEN1 (0.47) | MEN1KMT2ALMNA | |
| SCHEMBL407809 | 0.78 | ALDH1A1 (0.56) | ALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL2054658 | 0.77 | KIF11 (0.55) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL20764440 | 0.77 | MEN1 (0.67) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL28533796 | 0.77 | EPHX2 (0.58) | MEN1KMT2AMAPTNPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112142619-B | 1, 1-cyclopropane dicarboxylic acid amide compound and preparation method and application thereof | 浙江工业大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-112142619-A | 1, 1-cyclopropane dicarboxylic acid amide compound and preparation method and application thereof | 浙江工业大学 | 2020-12-29 | — | — | CN | disclosed |