Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29902892 | 1.00 | ATM (0.51) | ATMTDP1LMNARECQLALDH1A1 | |
| SCHEMBL3131783 | 0.87 | LMNA (0.54) | LMNARECQLALDH1A1MEN1KMT2A | |
| SCHEMBL30783383 | 0.87 | LMNA (0.54) | LMNARECQLALDH1A1MEN1KMT2A | |
| SCHEMBL2729354 | 0.85 | TDP1 (0.53) | ATMTDP1LMNARECQLALDH1A1 | |
| SCHEMBL5674809 | 0.85 | TDP1 (0.53) | ATMTDP1LMNARECQLALDH1A1 | |
| SCHEMBL4684043 | 0.85 | CASP6 (0.49) | TDP1LMNAALDH1A1CA2MAPT | |
| Methane SCHEMBL28528368 | 0.84 | TDP1 (0.51) | ATMTDP1LMNARECQLALDH1A1 | |
| SCHEMBL29100216 | 0.84 | ATM (0.51) | ATMTDP1LMNARECQLALDH1A1 | |
| SCHEMBL5184754 | 0.82 | GPR35 (0.51) | TDP1LMNARECQLALDH1A1CA2 | |
| SCHEMBL4101251 | 0.82 | CA2 (0.43) | LMNAALDH1A1CA2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087655-A | Benzimidazole derivatives | 辉瑞公司 | 2022-09-20 | — | — | CN | disclosed |