Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857856 | 0.92 | TSHR (0.49) | ALDH1A1SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL2850868 | 0.91 | ALDH1A1 (0.51) | ABCB1ALDH1A1SMN1; SMN2TP53CA12 | |
| SCHEMBL2860669 | 0.90 | TAAR1 (0.46) | ABCB1ALDH1A1CNR1LMNATP53 | |
| SCHEMBL2857600 | 0.88 | CNR1 (0.46) | ABCB1GAACNR1TP53 | |
| SCHEMBL2848475 | 0.88 | CNR1 (0.48) | ABCB1GAACNR1TP53 | |
| SCHEMBL2853462 | 0.88 | TRPV1 (0.42) | ABCB1CNR1 | |
| SCHEMBL2863131 | 0.88 | CNR1 (0.50) | ABCB1CNR1CA1CA2 | |
| SCHEMBL2852839 | 0.87 | SLC7A5 (0.40) | ABCB1ALDH1A1LMNA | |
| SCHEMBL2852505 | 0.86 | ABCB1 (0.48) | ABCB1GAAALDH1A1CNR1LMNA | |
| SCHEMBL2860458 | 0.86 | TP53 (0.46) | CNR1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |