Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.80 |
| ▸ | GAA | P10253 | 5/20 | 0.80 |
| ▸ | POLB | P06746 | 1/20 | 0.80 |
| ▸ | MEN1 | O00255 | 7/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | GFER | P55789 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | ALPI | P09923 | 1/20 | 0.61 |
| ▸ | ALPG | P10696 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28517560 | 0.89 | MAPT (1.00) | MAPTGAAPOLBMEN1KMT2A | |
| SCHEMBL8298517 | 0.84 | NOX4 (0.79) | MAPTGAAPOLBMEN1KMT2A | |
| SCHEMBL28510033 | 0.84 | NOX4 (0.79) | MAPTGAAPOLBMEN1KMT2A | |
| SCHEMBL8299903 | 0.84 | GAA (0.77) | MAPTGAAPOLBMEN1KMT2A | |
| SCHEMBL28515477 | 0.83 | MAPT (1.00) | MAPTGAAPOLBMEN1KMT2A | |
| SCHEMBL28512241 | 0.81 | MAPT (0.84) | MAPTGAAPOLBMEN1KMT2A | |
| SCHEMBL8299897 | 0.80 | MEN1 (0.73) | MAPTGAAPOLBMEN1KMT2A | |
| SCHEMBL28510030 | 0.80 | LMNA (0.76) | MAPTGAAPOLBMEN1KMT2A | |
| SCHEMBL28513870 | 0.79 | GAA (0.82) | MAPTGAAPOLBMEN1KMT2A | |
| SCHEMBL11974513 | 0.79 | GAA (0.63) | MAPTGAAPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112079744-A | Aromatic acylhydrazone derivatives and application thereof as NA (adenosine) inhibitor | 湖南大学 | 2020-12-15 | — | — | CN | claimed |
| CN-112079744-B | Aromatic acylhydrazone derivatives and application thereof as NA (adenosine) inhibitor | 湖南大学 | 2021-07-30 | — | — | CN | disclosed |
| CN-112079744-A | Aromatic acylhydrazone derivatives and application thereof as NA (adenosine) inhibitor | 湖南大学 | 2020-12-15 | — | — | CN | disclosed |