Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 4/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 4/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL28529141 | 1.00 | FDPS (0.46) | FDPSDNM1S1PR2S1PR1S1PR3 | |
| Phosphoric Acid SCHEMBL28290084 | 0.97 | FDPS (0.48) | FDPSDNM1S1PR2S1PR1S1PR3 | |
| Phosphoric Acid SCHEMBL28237161 | 0.97 | FDPS (0.48) | FDPSDNM1S1PR2S1PR1S1PR3 | |
| Phosphoric Acid SCHEMBL28072294 | 0.82 | CA2 (0.47) | FDPSS1PR2S1PR1S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL358300 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL28384375 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL3697304 | 0.82 | — | — | |
| Phosphoric Acid SCHEMBL29166404 | 0.81 | DNM1 (0.55) | FDPSDNM1S1PR2S1PR1S1PR3 | |
| Phosphoric Acid SCHEMBL28620622 | 0.81 | DNM1 (0.55) | FDPSDNM1S1PR2S1PR1S1PR3 | |
| Phosphoric Acid SCHEMBL28629987 | 0.79 | DNM1 (0.67) | FDPSDNM1S1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112402301-A | Silicone-oil-free shampoo composition with softening and repairing effects and preparation method and application thereof | 天津郁美净集团有限公司 | 2021-02-26 | — | — | CN | claimed |
| CN-112402301-A | Silicone-oil-free shampoo composition with softening and repairing effects and preparation method and application thereof | 天津郁美净集团有限公司 | 2021-02-26 | — | — | CN | disclosed |
| CN-112402301-A | Silicone-oil-free shampoo composition with softening and repairing effects and preparation method and application thereof | 天津郁美净集团有限公司 | 2021-02-26 | — | — | CN | disclosed |