Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.56 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ATP4A | P20648 | 1/20 | 0.42 |
| ▸ | ATP4B | P51164 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28520492 | 0.80 | MGLL (0.53) | ENPP2HSD17B1HSD17B2ALDH1A1DYRK1A | |
| SCHEMBL28528851 | 0.80 | HSD17B1 (0.41) | HSD17B1HSD17B2ALDH1A1MAPTHSD17B10 | |
| SCHEMBL1180286 | 0.79 | HSD17B1 (0.56) | HSD17B1HSD17B2HDAC6ALDH1A1MAPT | |
| SCHEMBL1180161 | 0.78 | HSD17B1 (0.52) | HSD17B1HSD17B2HDAC6ALDH1A1MAPT | |
| SCHEMBL28060965 | 0.77 | ENPP2 (0.85) | ENPP2HSD17B2HDAC4HDAC8DYRK1A | |
| SCHEMBL28574792 | 0.76 | HSD17B1 (0.51) | HSD17B1HSD17B2HDAC6ALDH1A1MAPT | |
| SCHEMBL20262887 | 0.76 | ENPP2 (0.65) | ENPP2HDAC4HDAC8DYRK1ACLK4 | |
| SCHEMBL1181055 | 0.75 | ABL1 (0.53) | HSD17B1HSD17B2HDAC6ALDH1A1HDAC4 | |
| SCHEMBL29742784 | 0.75 | HSD17B1 (0.67) | HSD17B1HSD17B2HDAC6ALDH1A1MAPT | |
| SCHEMBL28635415 | 0.75 | HSD17B1 (0.67) | HSD17B1HSD17B2HDAC6ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602834-B | Bruton's tyrosine kinase inhibitor | 北京盛诺基医药科技股份有限公司 | 2021-01-08 | — | — | CN | disclosed |