SCHEMBL28529323

SCHEMBL28529323

C=C(C(=O)OC)c1c([N+](=O)[O-])ccc(OC)c1OCc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSV O60911 2/20 0.50
CTSL P07711 2/20 0.50
HTR1A P08908 1/20 0.49
ADRA1D P25100 1/20 0.49
ADRA1A P35348 1/20 0.49
ADRA1B P35368 1/20 0.49
MEN1 O00255 6/20 0.48
KMT2A Q03164 6/20 0.48
MAPT P10636 4/20 0.48
ALDH1A1 P00352 2/20 0.45
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
ABCB1 P08183 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
HTT P42858 2/20 0.43
GAA P10253 1/20 0.43
CRHBP P24387 1/20 0.43
CRHR2 Q13324 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3276594 0.86 CTSV (0.53) CTSVCTSLHTR1AADRA1DADRA1A
SCHEMBL12151484 0.79 HTR1A (0.59) CTSVCTSLHTR1AADRA1DADRA1A
SCHEMBL4883017 0.75 HTR1A (0.55) CTSVCTSLHTR1AADRA1DADRA1A
SCHEMBL21815059 0.74 HTR1A (0.54) CTSVCTSLHTR1AADRA1DADRA1A
SCHEMBL7822540 0.73 CTSV (0.53) CTSVCTSLHTR1AADRA1DADRA1A
SCHEMBL9315352 0.73 MAPT (0.56) CTSVCTSLHTR1AADRA1DADRA1A
SCHEMBL9315348 0.73 MAPT (0.56) CTSVCTSLHTR1AADRA1DADRA1A
SCHEMBL30524610 0.73 LMNA (0.49) CTSVCTSLHTR1AADRA1DADRA1A
SCHEMBL9315201 0.72 HTR1A (0.47) CTSVCTSLHTR1AADRA1DADRA1A
SCHEMBL11067298 0.72 HTR1A (0.54) CTSVCTSLHTR1AADRA1DADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111808031-B Ferulic acid derivative and preparation method and application thereof 湖南中医药大学 2022-01-14 CN disclosed
CN-111808031-A Ferulic acid derivative and preparation method and application thereof 湖南中医药大学 2020-10-23 CN disclosed