Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK11 | Q15759 | 4/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.58 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.58 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.58 |
| ▸ | MAP3K20 | Q9NYL2 | 2/20 | 0.58 |
| ▸ | MAP3K2 | Q9Y2U5 | 2/20 | 0.58 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.47 |
| ▸ | MLYCD | O95822 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856270 | 0.92 | MAPK14 (0.56) | MAPK11MAPK14DDR1DDR2MAP3K20 | |
| SCHEMBL2854446 | 0.91 | MAPK11 (0.55) | MAPK11MAPK14DDR1DDR2MAP3K20 | |
| SCHEMBL2852950 | 0.90 | MAPK14 (0.67) | MAPK11MAPK14DDR1DDR2MAP3K20 | |
| SCHEMBL2853087 | 0.88 | MAPK11 (0.53) | MAPK11MAPK14DDR1DDR2MAP3K20 | |
| SCHEMBL2856647 | 0.87 | MAPK11 (0.52) | MAPK11MAPK14DDR1DDR2MAP3K20 | |
| SCHEMBL2860624 | 0.82 | SPR (0.57) | MAPK11MAPK14DDR1DDR2MAP3K20 | |
| SCHEMBL2854430 | 0.80 | MAPK11 (0.47) | MAPK11MAPK14DDR1DDR2MAP3K20 | |
| SCHEMBL2850254 | 0.79 | CNR2 (0.52) | MAPK11MAPK14DDR1DDR2MAP3K20 | |
| SCHEMBL2852100 | 0.77 | MAPK11 (0.49) | MAPK11MAPK14DDR1DDR2MAP3K20 | |
| SCHEMBL2850153 | 0.77 | KDM4E (0.63) | MAPK11MAPK14DDR1DDR2MAP3K20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |