Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK11 | Q15759 | 3/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.53 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.53 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.53 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.53 |
| ▸ | MAP3K2 | Q9Y2U5 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.46 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856270 | 0.88 | MAPK14 (0.56) | MAPK11MAPK14DDR1DDR2TMEM97 | |
| SCHEMBL2853007 | 0.88 | MAPK11 (0.58) | MAPK11MAPK14DDR1DDR2TMEM97 | |
| SCHEMBL2854446 | 0.87 | MAPK11 (0.55) | MAPK11MAPK14DDR1DDR2TMEM97 | |
| SCHEMBL2852950 | 0.87 | MAPK14 (0.67) | MAPK11MAPK14DDR1DDR2TMEM97 | |
| SCHEMBL2927664 | 0.86 | CTSL (0.58) | POLBKDM4EALDH1A1TP53LMNA | |
| SCHEMBL2854367 | 0.84 | SPR (0.56) | MAPK11MAPK14DDR1DDR2TMEM97 | |
| SCHEMBL2856647 | 0.83 | MAPK11 (0.52) | MAPK11MAPK14DDR1DDR2TMEM97 | |
| SCHEMBL10366447 | 0.83 | TRPC3 (0.62) | MAPK14POLBKDM4EALDH1A1TP53 | |
| SCHEMBL10364511 | 0.81 | HSD11B1 (0.53) | MAPK14POLBKDM4EALDH1A1LMNA | |
| SCHEMBL10367050 | 0.80 | ALDH1A1 (0.55) | MAPK14POLBKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |