Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK11 | Q15759 | 2/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.47 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.47 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.47 |
| ▸ | MAP3K2 | Q9Y2U5 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 5/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850365 | 0.84 | SPR (0.53) | MAPK11MAPK14DDR1DDR2TMEM97 | |
| SCHEMBL2854446 | 0.83 | MAPK11 (0.55) | MAPK11MAPK14DDR1DDR2TMEM97 | |
| SCHEMBL2852950 | 0.81 | MAPK14 (0.67) | MAPK11MAPK14DDR1DDR2TMEM97 | |
| SCHEMBL2853007 | 0.80 | MAPK11 (0.58) | MAPK11MAPK14DDR1DDR2TMEM97 | |
| SCHEMBL2856270 | 0.80 | MAPK14 (0.56) | MAPK11MAPK14DDR1DDR2TMEM97 | |
| SCHEMBL2850254 | 0.80 | CNR2 (0.52) | MAPK11MAPK14DDR1DDR2TMEM97 | |
| SCHEMBL2852810 | 0.77 | KDM4E (0.48) | MAPK11MAPK14DDR1DDR2TMEM97 | |
| SCHEMBL2856252 | 0.77 | P2RX1 (0.49) | MLYCDTRPC3 | |
| SCHEMBL2855644 | 0.77 | ALDH1A1 (0.44) | KDM4EALDH1A1TRPC3KMT2AMAPT | |
| SCHEMBL2848180 | 0.77 | CCR1 (0.51) | MAPK11MAPK14DDR1DDR2TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |