Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TCF4 | P15884 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28536156 | 0.79 | NISCH (0.47) | MAPTSMN1; SMN2ALDH1A1TSHRNPC1 | |
| SCHEMBL4041670 | 0.75 | MTOR (0.41) | ALDH1A1HSD17B10KDM4ENPC1RAB9A | |
| SCHEMBL4049587 | 0.75 | ALDH1A1 (0.41) | MAPTSMN1; SMN2ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL28527366 | 0.74 | KDM4E (0.46) | MAPTSMN1; SMN2ALDH1A1NOX1AURKA | |
| SCHEMBL403894 | 0.74 | MTOR (0.43) | MAPTALDH1A1ALOX15KDM4ENPC1 | |
| SCHEMBL10866586 | 0.72 | MAPT (0.44) | MAPTSMN1; SMN2ALDH1A1ALOX15TSHR | |
| SCHEMBL1119442 | 0.70 | GFER (0.46) | KDM4ENPC1RAB9AKIF11NOTUM | |
| SCHEMBL11053022 | 0.70 | MAPT (0.50) | MAPTSMN1; SMN2ALDH1A1ALOX15TSHR | |
| SCHEMBL2090572 | 0.69 | ALDH1A1 (0.33) | MAPTSMN1; SMN2ALDH1A1ALOX15TSHR | |
| SCHEMBL771362 | 0.68 | NISCH (0.63) | MAPTSMN1; SMN2ALDH1A1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396505-A | Methods of treating inflammation | 维鲁公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-115379835-A | Methods of treating coronavirus | 维鲁公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-112512522-A | Compounds for the treatment of triple negative breast and ovarian cancer | 田纳西大学研究基金会 | 2021-03-16 | — | — | CN | disclosed |
| CN-112437664-A | Compounds for the treatment of pancreatic cancer | 田纳西大学研究基金会 | 2021-03-02 | — | — | CN | disclosed |