Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28908587 | 0.86 | PTPN1 (0.43) | APPMEN1KMT2ASMPD1HDAC1 | |
| SCHEMBL27997996 | 0.83 | HDAC8 (0.48) | APPKDM4EALDH1A1MAPTHDAC8 | |
| SCHEMBL28208251 | 0.81 | HDAC8 (0.49) | KDM4EMAPTSMPD1HDAC1HDAC8 | |
| SCHEMBL28414248 | 0.80 | HDAC8 (0.48) | MEN1KMT2AKDM4EMAPTSMPD1 | |
| SCHEMBL15239366 | 0.76 | MEN1 (0.43) | MEN1KMT2ATHRBKDM4EHPGD | |
| SCHEMBL29136858 | 0.75 | ERN1 (0.40) | KMT2ATHRBKDM4EALDH1A1HPGD | |
| SCHEMBL28525364 | 0.75 | ERN1 (0.50) | THRBKDM4EALDH1A1GAAMAPT | |
| SCHEMBL6958225 | 0.75 | ERN1 (0.50) | MEN1KMT2ATHRBKDM4EALDH1A1 | |
| SCHEMBL3676845 | 0.75 | THRB (0.39) | MEN1KMT2ATHRBKDM4EALDH1A1 | |
| SCHEMBL7426748 | 0.74 | KMT2A (0.50) | APPMEN1KMT2ATHRBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108084030-B | Phenylpropanoid ester compound and preparation method and application thereof | 苏州沪云新药研发股份有限公司 | 2021-08-31 | — | — | CN | disclosed |
| CN-108047048-B | Phenylpropanoate compound and preparation method and application thereof | 苏州沪云肿瘤研究中心股份有限公司 | 2021-01-12 | — | — | CN | disclosed |