Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.33 |
| ▸ | RELA | Q04206 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28525364 | 0.78 | ERN1 (0.50) | THRBERN1ALDH1A1KDM4EPTGS1 | |
| SCHEMBL29136858 | 0.78 | ERN1 (0.40) | THRBERN1THRAALDH1A1RXFP1 | |
| SCHEMBL27519352 | 0.77 | MAPT (0.48) | THRBTHRAALDH1A1L3MBTL1KDM4E | |
| SCHEMBL15239366 | 0.77 | MEN1 (0.43) | THRBTHRAKDM4EHPGDLMNA | |
| SCHEMBL29135178 | 0.75 | PTPN1 (0.42) | THRBERN1THRAALDH1A1RXFP1 | |
| SCHEMBL28530588 | 0.75 | APP (0.45) | THRBTHRAALDH1A1KDM4EHPGD | |
| SCHEMBL24810564 | 0.74 | NFE2L2 (0.47) | THRBERN1THRAALDH1A1KDM4E | |
| SCHEMBL28295437 | 0.74 | ABCG2 (0.45) | THRBTHRAALDH1A1KDM4EPTGS1 | |
| SCHEMBL30406222 | 0.73 | ALDH1A1 (0.53) | THRBALDH1A1KDM4EPTGS1HPGD | |
| SCHEMBL31339995 | 0.72 | THRB (0.39) | THRBTHRAKDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120321533-A1 | CATALYST | ALMQVIST FREDRIK (SE) | 2012-12-20 | — | — | US | disclosed |
| EP-2152410-A2 | PROCESS FOR THE PRODUCTION OF PALLADIUM SUPPORTED CATALYSTS FOR CATALYZING HECK, SUZUKI-MIYAURA SONOGASHIRA COUPLING AND BUCHWALD-HARTWIG REACTIONS | Nordic chemquest Aktiebolag (SE) | 2010-02-17 | — | — | EP | disclosed |
| EP-1994983-A1 | Catalyst containing covalently bonded formate groups and Pd(0) and process for its obtention | Almquest AB (SE) | 2008-11-26 | — | — | EP | disclosed |
| WO-2008138938-A2 | PROCESS FOR THE PRODUCTION OF PALLADIUM SUPPORTED CATALYSTS FOR CATALYZING HECK, SUZUKI-MIYAURA SONOGASHIRA COUPLING AND BUCHWALD-HARTWIG REACTIONS | NORDIC CHEMQUEST AB (SE) | 2008-11-20 | — | — | WO | disclosed |