Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28525364 | 0.85 | ERN1 (0.50) | ERN1ALDH1A1THRBTSHRAPOBEC3A | |
| SCHEMBL15239366 | 0.80 | MEN1 (0.43) | THRBKDM4ETUBB1KMT2AHPGD | |
| SCHEMBL3676845 | 0.78 | THRB (0.39) | ERN1ALDH1A1THRBKDM4ERXFP1 | |
| SCHEMBL28783574 | 0.77 | TSHR (0.43) | ERN1ALDH1A1TSHRAPOBEC3AHTT | |
| SCHEMBL30406222 | 0.76 | ALDH1A1 (0.53) | ALDH1A1THRBKDM4ETUBB1PTGS1 | |
| SCHEMBL27368124 | 0.76 | ACHE (0.50) | ERN1ALDH1A1HTTKDM4ETUBB1 | |
| SCHEMBL29135178 | 0.75 | PTPN1 (0.42) | ERN1ALDH1A1THRBKDM4ERXFP1 | |
| SCHEMBL147312 | 0.74 | TUBB1 (0.46) | ERN1ALDH1A1TSHRAPOBEC3AHTT | |
| SCHEMBL24810564 | 0.74 | NFE2L2 (0.47) | ERN1ALDH1A1THRBKDM4EKMT2A | |
| SCHEMBL28295437 | 0.74 | ABCG2 (0.45) | ALDH1A1THRBKDM4ETUBB1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355521-A | Heteroaryl inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-05 | — | — | CN | disclosed |