SCHEMBL28530618

SCHEMBL28530618

C=CCC(CCCO)OC(N)=O

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.30
GRIK2 Q13002 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29789534 0.81 TSHR (0.42)
SCHEMBL28529440 0.81 GRIK1 (0.33) GRIK1GRIK2
SCHEMBL28533294 0.81 GRIK1 (0.33) GRIK1GRIK2
SCHEMBL28529438 0.81 GRIK1 (0.33) GRIK1GRIK2
SCHEMBL28522874 0.79 MAPT (0.33)
SCHEMBL9230199 0.77 GPR84 (0.33)
SCHEMBL16500086 0.77
SCHEMBL29102854 0.76 GRIK1 (0.32) GRIK1GRIK2
SCHEMBL11752280 0.74 CTSK (0.39) GRIK1GRIK2
SCHEMBL28821460 0.74 LMNA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112351778-B Fused tricyclic heterocycles and therapeutic uses thereof 江苏恒瑞医药股份有限公司 2023-04-04 CN disclosed
CN-113195473-B Tricyclic compound as STING agonist and preparation method and medical application thereof 江苏恒瑞医药股份有限公司 2022-11-22 CN disclosed
CN-113195473-A Tricyclic compound as STING agonist and preparation method and medical application thereof 江苏恒瑞医药股份有限公司 2021-07-30 CN disclosed
CN-112351778-A Fused tricyclic heterocycles and therapeutic uses thereof 江苏恒瑞医药股份有限公司 2021-02-09 CN disclosed