Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | DDX3X | O00571 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30737482 | 0.84 | MEN1 (0.65) | HTR6MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL28271817 | 0.84 | MEN1 (0.65) | HTR6MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL9616784 | 0.83 | HTR6 (0.54) | HTR6MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL28513321 | 0.83 | MEN1 (0.59) | HTR6MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL9616781 | 0.80 | WDR5 (0.57) | HTR6MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL28506098 | 0.80 | HTR6 (0.61) | HTR6MEN1KMT2APOLBGAA | |
| SCHEMBL29530798 | 0.80 | HTR6 (0.61) | HTR6MEN1KMT2APOLBPKM | |
| SCHEMBL28270279 | 0.80 | HTR6 (0.61) | HTR6MEN1KMT2APOLBGAA | |
| SCHEMBL28270280 | 0.80 | HTR6 (0.61) | HTR6MEN1KMT2APOLBPKM | |
| SCHEMBL28270290 | 0.80 | HTR6 (0.61) | HTR6MEN1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109081793-B | Sulfonamide urease inhibitor and preparation method and application thereof | 吉首大学 | 2021-03-30 | — | — | CN | disclosed |
| CN-109096156-B | Disulfonyl meta-aryl diamine urease inhibitor and preparation method and application thereof | 吉首大学 | 2021-01-15 | — | — | CN | disclosed |