Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | PAICS | P22234 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | NEK2 | P51955 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18423522 | 0.87 | TDO2 (0.47) | TDO2PAICSHRH1DDB1CRBN | |
| Trifluoroacetic Acid SCHEMBL943761 | 0.85 | TDO2 (0.46) | TDO2PAICSHRH1TIPARPNAMPT | |
| Trifluoroacetic Acid SCHEMBL1928035 | 0.84 | DGAT1 (0.47) | TDO2PAICSHRH1TIPARPLIPG | |
| Trifluoroacetic Acid SCHEMBL26620566 | 0.77 | LIPG (0.49) | PAICSLIPG | |
| SCHEMBL943763 | 0.77 | TDO2 (0.45) | TDO2PAICSHRH1TIPARP | |
| SCHEMBL14127773 | 0.75 | MAPT (0.49) | TDO2PAICSHRH1L3MBTL1 | |
| SCHEMBL18423411 | 0.74 | NAMPT (0.47) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL2252998 | 0.74 | MAPT (0.41) | TDO2PAICSSMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL2257085 | 0.74 | MAPT (0.41) | TDO2PAICSSMN1; SMN2 | |
| SCHEMBL942217 | 0.73 | LIPE (0.50) | TDO2TIPARPHTR2CKMT2ALIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107849017-B | 1,1, 1-trifluoro-3-hydroxypropan-2-ylcarbamate derivatives and 1,1, 1-trifluoro-4-hydroxybutyl-2-ylcarbamate derivatives as MAGL inhibitors | 辉瑞公司 | 2021-03-30 | — | — | CN | disclosed |