Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28529253 | 1.00 | ENPP2 (0.42) | ENPP2HTR1ANOTUMSERPINE1SLC6A9 | |
| SCHEMBL28543121 | 0.87 | MMP2 (0.45) | ENPP2HTR1AMAPTPOLB | |
| SCHEMBL28547111 | 0.87 | MMP2 (0.45) | ENPP2HTR1AMAPTPOLB | |
| SCHEMBL28543125 | 0.87 | MMP2 (0.45) | ENPP2HTR1AMAPTPOLB | |
| SCHEMBL28525708 | 0.82 | ENPP2 (0.44) | ENPP2HTR1ASLC6A9SLC6A5TGM2 | |
| SCHEMBL28531773 | 0.82 | ENPP2 (0.44) | ENPP2HTR1ASLC6A9SLC6A5TGM2 | |
| SCHEMBL28547080 | 0.78 | ENPP2 (0.40) | ENPP2HTR1ATGM2MAPTACHE | |
| SCHEMBL28542506 | 0.78 | ENPP2 (0.40) | ENPP2HTR1ATGM2MAPTACHE | |
| SCHEMBL13570060 | 0.77 | ENPP2 (0.44) | ENPP2HTR1ASLC6A9SLC6A5TGM2 | |
| SCHEMBL28537640 | 0.77 | ENPP2 (0.44) | ENPP2HTR1ASLC6A9SLC6A5TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-112513021-A | ROR gamma antagonist and application thereof in medicine | 广东东阳光药业有限公司 | 2021-03-16 | — | — | CN | disclosed |