Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28525708 | 0.90 | ENPP2 (0.44) | ENPP2HTR1ATGM2SLC18A3HTR2C | |
| SCHEMBL28531773 | 0.90 | ENPP2 (0.44) | ENPP2HTR1ATGM2SLC18A3HTR2C | |
| SCHEMBL28526930 | 0.85 | HTR1A (0.39) | ENPP2HTR1ATGM2ALDH1A1POLB | |
| SCHEMBL23632290 | 0.82 | SRD5A2 (0.43) | HTR1A | |
| SCHEMBL21616646 | 0.82 | SRD5A2 (0.43) | HTR1A | |
| SCHEMBL21616615 | 0.80 | HSD11B1 (0.42) | HTR2C | |
| SCHEMBL23632362 | 0.80 | HSD11B1 (0.42) | HTR2C | |
| SCHEMBL23632570 | 0.79 | ALDH1A1 (0.45) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL28534482 | 0.79 | ALDH1A1 (0.45) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL28547080 | 0.79 | ENPP2 (0.40) | ENPP2HTR1ATGM2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-112513021-A | ROR gamma antagonist and application thereof in medicine | 广东东阳光药业有限公司 | 2021-03-16 | — | — | CN | disclosed |