Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853232 | 0.86 | CCR1 (0.48) | KDM4EALDH1A1TRPV1MAPTNPC1 | |
| SCHEMBL2858063 | 0.82 | MAPT (0.57) | KDM4EALDH1A1TRPV1P2RX7MAPT | |
| SCHEMBL2850019 | 0.82 | ROCK2 (0.46) | ALDH1A1TRPV1NTRK1P2RX7MAPT | |
| SCHEMBL2880130 | 0.81 | MAPK1 (0.54) | TRPV1MAPTNPC1RAB9ANPSR1 | |
| SCHEMBL2857827 | 0.80 | MEN1 (0.55) | KDM4EALDH1A1TRPV1MAPTNPC1 | |
| SCHEMBL2850439 | 0.80 | KMT2A (0.53) | NPC1RAB9A | |
| SCHEMBL2856146 | 0.80 | CNR1 (0.53) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL2854169 | 0.79 | MAPT (0.56) | KDM4EALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL2880891 | 0.79 | CNR1 (0.54) | KDM4EMAPTNPC1RAB9ANPSR1 | |
| SCHEMBL2854401 | 0.79 | RAB9A (0.46) | KDM4EALDH1A1TRPV1P2RX7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |