Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.67 |
| ▸ | NPC1 | O15118 | 10/20 | 0.67 |
| ▸ | PKM | P14618 | 2/20 | 0.67 |
| ▸ | NAMPT | P43490 | 1/20 | 0.60 |
| ▸ | KDR | P35968 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2860254 | 0.89 | RAB9A (0.60) | RAB9ANPC1PKMKDRSMN1; SMN2 | |
| SCHEMBL2857605 | 0.84 | ALDH1A1 (0.61) | KDRSMN1; SMN2KDM4EMAPTMEN1 | |
| SCHEMBL2852188 | 0.84 | KDM4E (0.58) | RAB9ANPC1KDRSMN1; SMN2KDM4E | |
| SCHEMBL2854574 | 0.82 | HSP90AA1 (0.51) | RAB9ANPC1PKMKDRSMN1; SMN2 | |
| SCHEMBL19748575 | 0.77 | KDR (0.81) | RAB9ANPC1KDRSMN1; SMN2KDM4E | |
| SCHEMBL2860286 | 0.77 | RAB9A (0.87) | RAB9ANPC1PKMNAMPTSMN1; SMN2 | |
| SCHEMBL2856280 | 0.76 | MAPK14 (0.55) | KDRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL12172758 | 0.76 | MAPT (0.75) | RAB9ANPC1KDRSMN1; SMN2KDM4E | |
| SCHEMBL2852805 | 0.75 | KDR (0.56) | KDRSMN1; SMN2KDM4EMAPTMEN1 | |
| SCHEMBL1507696 | 0.75 | MAPT (0.78) | RAB9ANPC1KDRSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |