Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.55 |
| ▸ | KDR | P35968 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PLEC | Q15149 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857605 | 0.91 | ALDH1A1 (0.61) | MAPK14KDRGAAALDH1A1POLB | |
| SCHEMBL2854503 | 0.84 | KDR (0.47) | MAPK14KDRGAAL3MBTL1ALDH1A1 | |
| SCHEMBL2854295 | 0.82 | MAPK14 (0.68) | MAPK14GAAALDH1A1POLBMAPT | |
| SCHEMBL2852805 | 0.81 | KDR (0.56) | KDRGAAL3MBTL1ALDH1A1MAPT | |
| SCHEMBL2850360 | 0.78 | MAPT (0.61) | MAPK14GAAALDH1A1POLBMAPT | |
| SCHEMBL14097125 | 0.77 | ALDH1A1 (0.67) | MAPK14GAAALDH1A1POLBMAPT | |
| SCHEMBL6338131 | 0.76 | MAPK14 (0.49) | MAPK14GAAALDH1A1POLBMAPT | |
| SCHEMBL2853250 | 0.76 | RAB9A (0.67) | KDRALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2850383 | 0.76 | KMT2A (0.47) | MAPK14KDRALDH1A1POLBMAPT | |
| SCHEMBL16615637 | 0.75 | POLB (0.52) | MAPK14GAAALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |