Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850858 | 0.92 | KDR (0.48) | HSP90AA1KDRMEN1KMT2AMAPT | |
| SCHEMBL2853256 | 0.86 | SMN1; SMN2 (0.46) | MEN1KMT2AMAPTSMN1; SMN2POLB | |
| SCHEMBL2854574 | 0.85 | HSP90AA1 (0.51) | HSP90AA1KDRMEN1KMT2AMAPT | |
| SCHEMBL2852188 | 0.83 | KDM4E (0.58) | KDRMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL2850871 | 0.82 | NPC1 (0.51) | KMT2AMAPTSMN1; SMN2POLBRAB9A | |
| SCHEMBL2857574 | 0.82 | MAPT (0.50) | MEN1KMT2AMAPTSMN1; SMN2POLB | |
| SCHEMBL2856355 | 0.81 | RAB9A (0.52) | KMT2AMAPTSMN1; SMN2POLBRAB9A | |
| SCHEMBL2860786 | 0.81 | MAPT (0.49) | MEN1KMT2AMAPTSMN1; SMN2POLB | |
| SCHEMBL2850383 | 0.81 | KMT2A (0.47) | HSP90AA1KDRMEN1KMT2AMAPT | |
| SCHEMBL2850763 | 0.81 | MAPT (0.48) | KMT2AMAPTSMN1; SMN2POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |