Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2853255 | 0.92 | HSP90AA1 (0.48) | KDRMEN1KMT2ACASP3SENP8 | |
| SCHEMBL2857584 | 0.89 | RAB9A (0.45) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL2852805 | 0.84 | KDR (0.56) | KDRL3MBTL1GAAMEN1KMT2A | |
| SCHEMBL2852552 | 0.83 | MEN1 (0.51) | MEN1KMT2AMAPTKDM4ENPSR1 | |
| SCHEMBL2854596 | 0.82 | TP53 (0.46) | GAAMEN1KMT2AMAPTKDM4E | |
| SCHEMBL2848541 | 0.82 | RAB9A (0.43) | L3MBTL1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL2857353 | 0.82 | CCR1 (0.47) | GAAMAPTTRPV1KDM4ESMN1; SMN2 | |
| SCHEMBL2854503 | 0.82 | KDR (0.47) | KDRL3MBTL1GAAMEN1KMT2A | |
| SCHEMBL2852636 | 0.82 | NPC1 (0.46) | L3MBTL1MEN1KMT2AHSP90AA1MAPT | |
| SCHEMBL2853256 | 0.82 | SMN1; SMN2 (0.46) | L3MBTL1MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |