Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 10/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15933941 | 0.76 | GPBAR1 (0.59) | GPBAR1NOTUMBRD4 | |
| SCHEMBL22605563 | 0.76 | HRH3 (0.47) | L3MBTL1 | |
| SCHEMBL28539044 | 0.71 | OPRL1 (0.38) | — | |
| Trifluoroacetic Acid SCHEMBL22587774 | 0.70 | GPBAR1 (0.44) | GPBAR1NOTUMBRD4 | |
| SCHEMBL22588234 | 0.70 | GPR119 (0.50) | GPBAR1 | |
| SCHEMBL22605561 | 0.70 | GPBAR1 (0.50) | GPBAR1NOTUMBRD4 | |
| SCHEMBL3277487 | 0.68 | SCN10A (0.37) | NOTUM | |
| SCHEMBL28527744 | 0.68 | IDH2 (0.40) | NOTUM | |
| SCHEMBL28527223 | 0.68 | HSD11B1 (0.42) | NOTUML3MBTL1 | |
| SCHEMBL330029 | 0.66 | ALDH1A1 (0.43) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848598-A | Heterocyclic ring-containing compound, application thereof and composition containing heterocyclic ring-containing compound | 健艾仕生物医药有限公司 | 2020-10-30 | — | — | CN | disclosed |