Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857073 | 0.94 | CCR1 (0.48) | CCR1KDM4EALDH1A1POLBMAPT | |
| SCHEMBL2852356 | 0.93 | CCR1 (0.48) | CCR1KDM4ECYP3A4MAPK1VNN1 | |
| SCHEMBL2863210 | 0.89 | CCR1 (0.50) | CCR1KDM4EMAPTTACR1MAPK1 | |
| SCHEMBL2860247 | 0.88 | CCR1 (0.59) | CCR1KDM4EALDH1A1POLBMAPT | |
| SCHEMBL2854847 | 0.87 | ALDH1A1 (0.48) | CCR1KDM4EALDH1A1POLBMAPT | |
| SCHEMBL2857994 | 0.87 | MTOR (0.46) | CCR1KDM4EALDH1A1MAPTTDP1 | |
| SCHEMBL2852454 | 0.87 | KDM4E (0.48) | CCR1KDM4EALDH1A1POLBMAPT | |
| SCHEMBL2861243 | 0.87 | KDM4E (0.52) | CCR1KDM4EALDH1A1POLBMAPT | |
| SCHEMBL2854804 | 0.85 | MAPK1 (0.48) | CCR1KDM4EALDH1A1POLBMAPT | |
| SCHEMBL2860715 | 0.85 | ALDH1A1 (0.46) | CCR1KDM4EALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |