Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850258 | 0.88 | MAPT (0.51) | MAPTNPSR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2852565 | 0.86 | MAPT (0.42) | MAPTRAB9ANPC1NPSR1MEN1 | |
| SCHEMBL2854572 | 0.86 | RAB9A (0.44) | MAPTRAB9ANPC1NPSR1MEN1 | |
| SCHEMBL2854221 | 0.86 | MAPT (0.51) | MAPTNPSR1MEN1KMT2AP2RX1 | |
| SCHEMBL2856514 | 0.85 | CCR1 (0.49) | ACHEMAPTRAB9ANPC1NPSR1 | |
| SCHEMBL2853258 | 0.85 | NPY5R (0.45) | MAPTRAB9ANPC1NPSR1MEN1 | |
| SCHEMBL2853385 | 0.85 | MAPT (0.42) | ACHEMAPTNPSR1MEN1KMT2A | |
| SCHEMBL2852360 | 0.85 | MAPT (0.42) | ACHEMAPTNPSR1MEN1KMT2A | |
| SCHEMBL2848615 | 0.85 | MAPT (0.44) | MAPTNPC1NPSR1MEN1KMT2A | |
| SCHEMBL2848317 | 0.84 | MAPT (0.46) | ACHEMAPTNPC1NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |