Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 8/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854244 | 0.89 | ACHE (0.52) | CCR1ACHEMAPTNPSR1RAB9A | |
| SCHEMBL2856460 | 0.87 | CCR1 (0.65) | CCR1ACHEMAPTNPSR1RAB9A | |
| SCHEMBL2849956 | 0.87 | CCR1 (0.62) | CCR1MAPTNPSR1LMNAHSP90AA1 | |
| SCHEMBL2854543 | 0.86 | CCR1 (0.54) | CCR1MAPTNPSR1RAB9ANPC1 | |
| SCHEMBL2861197 | 0.86 | CCR1 (0.51) | CCR1ACHEMAPTNPSR1RAB9A | |
| SCHEMBL2853364 | 0.85 | CCR1 (0.52) | CCR1ACHEMAPTNPSR1RAB9A | |
| SCHEMBL2853388 | 0.85 | CCR1 (0.48) | CCR1MAPTRAB9ANPC1KDM4E | |
| SCHEMBL2856212 | 0.85 | CCR1 (0.47) | CCR1ACHEMAPTNPSR1RAB9A | |
| SCHEMBL2854508 | 0.85 | CCR1 (0.62) | CCR1AKR1B1ACHEMAPTNPSR1 | |
| SCHEMBL2856294 | 0.85 | CCR1 (0.49) | CCR1KDM4EALDH1A1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |