Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | ICMT | O60725 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5547476 | 0.84 | ALDH1A1 (0.54) | KMT2AMEN1KDM4EALDH1A1RAB9A | |
| SCHEMBL5550694 | 0.82 | ALDH1A1 (0.53) | KMT2AMEN1KDM4EALDH1A1RAB9A | |
| Salicyladehyde SCHEMBL28708651 | 0.82 | DDX3X (0.45) | KMT2AMEN1KDM4ECYP3A4CYP2D6 | |
| SCHEMBL8306103 | 0.82 | KMT2A (0.58) | KMT2AMEN1KDM4ECYP3A4CYP2D6 | |
| SCHEMBL28533950 | 0.79 | KMT2A (0.49) | KMT2AMEN1KDM4ECYP2D6ALDH1A1 | |
| SCHEMBL5551984 | 0.79 | ALDH1A1 (0.47) | KMT2AMEN1KDM4ECYP3A4CYP2D6 | |
| SCHEMBL7550241 | 0.79 | KMT2A (0.54) | KMT2ACYP3A4CYP2C19ALDH1A1RAB9A | |
| SCHEMBL10891076 | 0.79 | POLB (0.54) | KDM4ECYP3A4CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL28676055 | 0.79 | ALDH1A1 (0.50) | KMT2AMEN1KDM4ECYP2D6CYP2C19 | |
| SCHEMBL28933514 | 0.79 | ALDH1A1 (0.36) | KMT2AMEN1KDM4ECYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118420612-A | Target protein degradation compound based on CDK4/6 inhibitor and preparation method and application thereof | 沈阳药科大学 | 2024-08-02 | — | — | CN | claimed |
| CN-115925647-A | Production method of linezolid | 湖北广济药业股份有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-114505036-A | Method and equipment for preparing linezolid | 程竹隐 | 2022-05-17 | — | — | CN | claimed |
| CN-108640888-B | Double-halogenated salicylaldehyde 3-fluoro-4-morpholinyl aniline Schiff base and preparation method and application thereof | 淮阴师范学院 | 2022-03-15 | — | — | CN | claimed |
| CN-112409286-A | Synthesis method of N-substituted phenyl-5-hydroxymethyl-2-oxazolidinone | 杭州迪克科技有限公司 | 2021-02-26 | — | — | CN | claimed |
| EP-3095777-B1 | LINEZOLID INTERMEDIATE AND METHOD FOR SYNTHESIZING LINEZOLID | ZHEJIANG MED XINCHANG PHARM (CN) | 2018-06-27 | — | — | EP | claimed |
| EP-3095777-A1 | LINEZOLID INTERMEDIATE AND METHOD FOR SYNTHESIZING LINEZOLID | ZheJiang Medicine Co., Ltd. Xinchang Pharmaceutical Factory (CN) | 2016-11-23 | — | — | EP | claimed |
| EP-2595968-B1 | NOVEL PROCESS FOR PREPARATION OF LINEZOLID AND ITS NOVEL INTERMEDIATES | LEE PHARMA LTD (IN) | 2015-09-09 | — | — | EP | claimed |
| US-8962827-B2 | Linezolid intermediate and method for synthesizing linezolid | ZHEJIANG MEDICINE CO. LTD. XINCHANG PHARMACEUTICAL FACTORY (CN) | 2015-02-24 | — | — | US | claimed |
| US-20140024827-A1 | LINEZOLID INTERMEDIATE AND METHOD FOR SYNTHESIZING LINEZOLID | ZHEJIANG MEDICINE CO., LTD XINCHANG PHARMACEUTICAL FACTORY (CN) | 2014-01-23 | — | — | US | claimed |
| EP-1737850-B1 | A NOVEL PROCESS FOR THE PREPARATION OF LINEZOLID AND RELATED COMPOUNDS | SYMED LABS LTD (IN) | 2007-10-03 | — | — | EP | claimed |
| CN-119161306-A | Bicycloacetamide structural compound, preparation method and pharmaceutical application thereof | 河南大学 | 2024-12-20 | — | — | CN | disclosed |
| CN-118772064-A | Pyrimidine compound containing nitrogen methoxy benzamide and preparation method and application thereof | 贵州大学 | 2024-10-15 | — | — | CN | disclosed |
| CN-118420612-A | Target protein degradation compound based on CDK4/6 inhibitor and preparation method and application thereof | 沈阳药科大学 | 2024-08-02 | — | — | CN | disclosed |
| CN-118290358-A | Method for preparing linezolid key intermediate (S) -5- ((benzylamino) methyl) oxazolidine-2-one | 江苏医药职业学院 | 2024-07-05 | — | — | CN | disclosed |
| WO-1999037630-A1 | OXAZOLIDINONE COMBINATORIAL LIBRARIES, COMPOSITIONS AND METHODS OF PREPARATION | VERSICOR, INC. (US) | 1999-07-29 | — | — | WO | disclosed |
| US-5880118-A | Substituted oxazine and thiazine oxazolidinone antimicrobials | PHARMACIA & UPJOHN COMPANY (US) | 1999-03-09 | — | — | US | disclosed |
| US-5688792-A | BACTERICIDES | PHARMACIA & UPJOHN COMPANY (US) | 1997-11-18 | — | — | US | disclosed |
| EP-0717738-A1 | SUBSTITUTED OXAZINE AND THIAZINE OXAZOLIDINONE ANTIMICROBIALS | PHARMACIA & UPJOHN COMPANY (US) | 1996-06-26 | — | — | EP | disclosed |
| WO-1995007271-A1 | SUBSTITUTED OXAZINE AND THIAZINE OXAZOLIDINONE ANTIMICROBIALS | THE UPJOHN COMPANY (US) | 1995-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140024827-A1 | LINEZOLID INTERMEDIATE AND METHOD FOR SYNTHESIZING LINEZOLID | CYP2C9, CYP3A4, CYP2C19 | KMT2A 246/4885MEN1 2309/4885KDM4E 2221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.