Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5550694 | 0.98 | ALDH1A1 (0.53) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL28533950 | 0.84 | KMT2A (0.49) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL5551984 | 0.84 | ALDH1A1 (0.47) | ALDH1A1KDM4EMEN1KMT2ASLC6A3 | |
| SCHEMBL2406119 | 0.84 | KMT2A (0.49) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL3544482 | 0.84 | POLB (0.44) | ALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL5547459 | 0.81 | KDM4E (0.44) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL5550835 | 0.80 | KDM4E (0.44) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL7125472 | 0.79 | KMT2A (0.39) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL7127198 | 0.78 | KMT2A (0.38) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL17287922 | 0.77 | NPC1 (0.62) | ALDH1A1SMN1; SMN2KDM4EKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077160-A | PHOTOCONDUCTIVE IMAGING MEMBERS WITH FLUORINATED SQUARAINE COMPOSITIONS | XEROX CORPORATION (US) | 1991-12-31 | — | — | US | claimed |
| JP-4229870-A | — | — | None | — | — | JP | disclosed |
| WO-2002000649-A9 | SUBSTITUTED QUINAZOLINE DERIVATIVES AND THEIR USE AS INHIBITORS | ASTRAZENECA AB (SE) | 2007-09-20 | — | — | WO | disclosed |
| EP-1299381-A1 | SUBSTITUTED QUINAZOLINE DERIVATIVES AND THEIR USE AS INHIBITORS | AstraZeneca AB (SE) | 2003-04-09 | — | — | EP | disclosed |
| WO-2002000649-A1 | SUBSTITUTED QUINAZOLINE DERIVATIVES AND THEIR USE AS INHIBITORS | ASTRAZENECA AB (SE) | 2002-01-03 | — | — | WO | disclosed |
| JP-H04229870-A | PHOTOCONDUCTIVE IMAGE FORMING MEMBER CONTAINING FLUORINATED SQUARINE COMPOUND | XEROX CORP | 1992-08-19 | — | — | JP | disclosed |
| US-5077160-A | PHOTOCONDUCTIVE IMAGING MEMBERS WITH FLUORINATED SQUARAINE COMPOSITIONS | XEROX CORPORATION (US) | 1991-12-31 | — | — | US | disclosed |