Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.58 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.50 |
| ▸ | UBE2N | P61088 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | SCN1A | P35498 | 1/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25456063 | 0.90 | CA12 (0.55) | BPTFHSD17B2KMT2AMEN1KDM4E | |
| Ethyltrimethoxy Benzoate SCHEMBL4410910 | 0.89 | KMT2A (0.66) | HSD17B2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL19351166 | 0.84 | HSD17B2 (0.58) | HSD17B2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL28534372 | 0.83 | TPMT (0.53) | BPTFKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL8351938 | 0.83 | HSD17B2 (0.65) | HSD17B2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7120174 | 0.82 | ALDH1A1 (0.81) | BPTFHSD17B2KMT2AMEN1KDM4E | |
| SCHEMBL5899536 | 0.79 | HSD17B2 (0.65) | HSD17B2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL6032945 | 0.79 | HSD17B2 (0.69) | HSD17B2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL582920 | 0.78 | HSD17B2 (0.68) | HSD17B2KMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL7122014 | 0.78 | LMNA (0.58) | BPTFKMT2AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1136198-C | Novel benzyl pyrimidines | ��������ҩ�ɷ�����˾ | 2004-01-28 | — | — | CN | disclosed |
| EP-0793656-B1 | NOVEL BENZYL PYRIMIDINES | BASILEA PHARMACEUTICA AG (CH) | 2003-03-26 | — | — | EP | disclosed |
| US-5763450-A | BACTERICIDES; TREATMENT OF INFECTIOUS DISEASES | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | disclosed |
| CN-1166831-A | Novel benzyl pyrimidines | HOFFMANN LA ROCHE (CH) | 1997-12-03 | — | — | CN | disclosed |
| EP-0793656-A1 | NOVEL BENZYL PYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 1997-09-10 | — | — | EP | disclosed |
| WO-1996016046-A2 | NOVEL BENZYL PYRIMIDINES | F. HOFFMANN-LA ROCHE AG (CH) | 1996-05-30 | — | — | WO | disclosed |