Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.41 |
| ▸ | ADH1A | P07327 | 5/20 | 0.39 |
| ▸ | ADH1C | P00326 | 3/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1358316 | 0.91 | TRPM8 (0.47) | TRPM8TRPA1EPHX1ADH1AADH1C | |
| SCHEMBL5412356 | 0.80 | TRPM8 (0.47) | TRPM8TRPA1EPHX1KCNA5ALDH1A1 | |
| SCHEMBL28012004 | 0.75 | ADH1A (0.47) | TRPM8TRPA1EPHX1ADH1AADH1C | |
| SCHEMBL27484514 | 0.75 | TRPM8 (0.42) | TRPM8TRPA1EPHX1ADH1AADH1C | |
| SCHEMBL15435867 | 0.74 | TRPM8 (0.52) | TRPM8TRPA1EPHX1KCNA5ALDH1A1 | |
| SCHEMBL26355350 | 0.74 | TRPM8 (0.52) | TRPM8TRPA1EPHX1KCNA5ALDH1A1 | |
| SCHEMBL2666136 | 0.73 | ADH1A (0.48) | TRPM8TRPA1EPHX1ADH1AADH1C | |
| SCHEMBL15435866 | 0.72 | TRPM8 (0.50) | TRPM8TRPA1EPHX1KCNA5ALDH1A1 | |
| SCHEMBL10642094 | 0.71 | TRPM8 (0.46) | TRPM8TRPA1EPHX1KCNA5ALDH1A1 | |
| SCHEMBL584097 | 0.71 | EPHX1 (0.44) | TRPM8TRPA1EPHX1KCNA5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384077-A | Solubilization of poorly soluble cooling substances | 西姆莱斯有限公司 | 2021-02-19 | — | — | CN | claimed |
| CN-112384077-A | Solubilization of poorly soluble cooling substances | 西姆莱斯有限公司 | 2021-02-19 | — | — | CN | disclosed |