SCHEMBL5412356

SCHEMBL5412356

C[CH]N(C1CC(C)CCC1C(C)C)C1CC(C)CCC1C(C)C

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 4/20 0.47
TRPA1 O75762 2/20 0.47
EPHX1 P07099 3/20 0.41
ALDH1A1 P00352 2/20 0.36
KCNA5 P22460 1/20 0.34
TRPV1 Q8NER1 3/20 0.31
LMNA P02545 2/20 0.31
NFE2L2 Q16236 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1358316 0.85 TRPM8 (0.47) TRPM8TRPA1EPHX1ALDH1A1KCNA5
SCHEMBL28534669 0.80 TRPM8 (0.43) TRPM8TRPA1EPHX1ALDH1A1KCNA5
SCHEMBL26355350 0.78 TRPM8 (0.52) TRPM8TRPA1EPHX1ALDH1A1KCNA5
SCHEMBL15435867 0.78 TRPM8 (0.52) TRPM8TRPA1EPHX1ALDH1A1KCNA5
SCHEMBL15435866 0.76 TRPM8 (0.50) TRPM8TRPA1EPHX1ALDH1A1KCNA5
SCHEMBL31105805 0.74 TRPM8 (0.48) TRPM8TRPA1EPHX1ALDH1A1KCNA5
SCHEMBL16445966 0.74 TRPM8 (0.48) TRPM8TRPA1EPHX1ALDH1A1KCNA5
SCHEMBL6335743 0.73 TRPM8 (0.52) TRPM8TRPA1EPHX1ALDH1A1KCNA5
SCHEMBL5307491 0.73 TRPM8 (0.47) TRPM8TRPA1EPHX1ALDH1A1KCNA5
SCHEMBL10642094 0.72 TRPM8 (0.46) TRPM8TRPA1EPHX1ALDH1A1KCNA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7250446-B2 Mercaptophenyl naphthyl methane compounds and synthesis thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2007-07-31 US claimed
US-20040229869-A1 Novel mercaptophenyl naphthyl methane compounds and synthesis thereof COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2004-11-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040229869-A1 Novel mercaptophenyl naphthyl methane compounds and synthesis thereof BRCA1, PGR, APC TRPM8 1803/4885TRPA1 2526/4885EPHX1 2615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.