SCHEMBL28534758

SCHEMBL28534758

Clc1ccccc1-c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.52
HTR7 P34969 5/20 0.47
HTR1A P08908 4/20 0.47
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
HTR2B P41595 1/20 0.41
CYP2A6 P11509 1/20 0.41
MAOA P21397 1/20 0.40
DPP4 P27487 1/20 0.39
HSP90AA1 P07900 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29394156 0.89 PNMT (0.53) PNMTHTR7HTR1ANPC1RAB9A
SCHEMBL3284763 0.89 PNMT (0.53) PNMTHTR7HTR1ANPC1RAB9A
Bromide SCHEMBL20542577 0.88 PNMT (0.52) PNMTHTR7HTR1ANPC1RAB9A
SCHEMBL30103334 0.87 PNMT (0.63) PNMTHTR7NPC1RAB9AHTR2B
SCHEMBL524602 0.87 PNMT (0.63) PNMTHTR7NPC1RAB9AHTR2B
SCHEMBL9126221 0.85 PGR (0.42) PNMTHTR7HTR1ANPC1RAB9A
SCHEMBL2877998 0.84 PNMT (0.61) PNMTHTR7NPC1RAB9AHTR2B
Nitrous Acid SCHEMBL20542585 0.80 HTR7 (0.47) PNMTHTR7HTR1ANPC1RAB9A
Cyclopentene SCHEMBL6255995 0.80 PNMT (0.45) PNMTHTR7HTR1ANPC1RAB9A
SCHEMBL4022045 0.78 PNMT (0.55) PNMTHTR7NPC1RAB9AHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112592464-B Two-dimensional conjugated 2-chlorophenyl fluorene copolymer photovoltaic material, preparation method and application 湖南文理学院 2023-10-31 CN claimed
CN-112592464-B Two-dimensional conjugated 2-chlorophenyl fluorene copolymer photovoltaic material, preparation method and application 湖南文理学院 2023-10-31 CN disclosed
CN-112592464-B Two-dimensional conjugated 2-chlorophenyl fluorene copolymer photovoltaic material, preparation method and application 湖南文理学院 2023-10-31 CN disclosed
CN-112592464-B Two-dimensional conjugated 2-chlorophenyl fluorene copolymer photovoltaic material, preparation method and application 湖南文理学院 2023-10-31 CN disclosed
CN-112592464-A Two-dimensional conjugated 2-chlorophenyl fluorene copolymer photovoltaic material, preparation method and application 湖南文理学院 2021-04-02 CN disclosed