Cyclopentene

Cyclopentene

SCHEMBL6255995

C1=CCCC1.Clc1cccc2c1Cc1ccccc1-2

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 2/20 0.45
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
HSP90AA1 P07900 1/20 0.38
HTR7 P34969 3/20 0.37
HTR2B P41595 1/20 0.37
HTR1A P08908 2/20 0.36
ACHE P22303 1/20 0.35
ADRA2A P08913 1/20 0.35
CYP2D6 P10635 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
ADRA1D P25100 1/20 0.35
ADRA1A P35348 1/20 0.35
ADRA1B P35368 1/20 0.35
EIF2AK1 Q9BQI3 1/20 0.34
MAOA P21397 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3284763 0.89 PNMT (0.53) PNMTNPC1RAB9AHSP90AA1HTR7
SCHEMBL29394156 0.89 PNMT (0.53) PNMTNPC1RAB9AHSP90AA1HTR7
Bromide SCHEMBL20542577 0.87 PNMT (0.52) PNMTNPC1RAB9AHSP90AA1HTR7
SCHEMBL28534758 0.80 PNMT (0.52) PNMTNPC1RAB9AHSP90AA1HTR7
Nitrous Acid SCHEMBL20542585 0.79 HTR7 (0.47) PNMTNPC1RAB9AHSP90AA1HTR7
Hexane SCHEMBL8572947 0.78 PNMT (0.47) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL23372304 0.77 MAOA (0.55) PNMTNPC1RAB9AHTR7HTR2B
Ether SCHEMBL9618978 0.77 PNMT (0.46) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL27688072 0.77 PNMT (0.49) PNMTNPC1RAB9AHSP90AA1HTR7
SCHEMBL9270180 0.75 MAOA (0.61) PNMTNPC1RAB9AACHEMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1017656-B1 METHOD FOR PRODUCING PERHALOGENATED CYCLOPENTENE CENTRAL GLASS CO LTD (JP) 2005-04-06 EP disclosed
EP-1017656-A1 METHOD FOR PRODUCING PERHALOGENATED CYCLOPENTENE Central Glass Company, Limited (JP) 2000-07-12 EP disclosed
WO-1999014173-A1 METHOD FOR PRODUCING PERHALOGENATED CYCLOPENTENE CENTRAL GLASS COMPANY, LIMITED (JP) 1999-03-25 WO disclosed