Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28694001 | 0.81 | IDO1 (0.51) | IDO1GPR84TUBB4ATUBBTUBA3C | |
| SCHEMBL31748732 | 0.80 | GPR84 (0.56) | IDO1GPR84TUBB4ATUBBTUBA3C | |
| SCHEMBL28150092 | 0.80 | TUBB4A (0.49) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28534743 | 0.80 | IDO1 (0.54) | IDO1GPR84TUBB4ATUBBTUBA3C | |
| SCHEMBL28099154 | 0.76 | SLC6A4 (0.46) | IDO1HTR2ASLC6A4HTR1AHTR6 | |
| SCHEMBL28544535 | 0.76 | TUBB4A (0.56) | IDO1GPR84TUBB4ATUBBTUBA3C | |
| SCHEMBL22802282 | 0.76 | IDO1 (0.62) | IDO1GPR84TUBB4ATUBBTUBA3C | |
| SCHEMBL4437539 | 0.75 | TUBB4A (0.55) | IDO1GPR84TUBB4ATUBBTUBA3C | |
| SCHEMBL28198221 | 0.75 | HTR7 (0.49) | HTR1AMEN1KMT2AHTR7HTR6 | |
| SCHEMBL22802281 | 0.75 | TUBB4A (0.63) | IDO1GPR84TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108863897-B | Synthesis method of trifluoromethyl thioetherified indole derivative | 天津师范大学 | 2021-08-31 | — | — | CN | disclosed |
| CN-108586312-B | Green sulfuration method of indole compound by using triphosgene as reducing agent | 丽水学院 | 2021-03-05 | — | — | CN | disclosed |