Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 2/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 4/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 6/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | SETD2 | Q9BYW2 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23581265 | 0.84 | LGMN (0.39) | LGMNL3MBTL3EGFRALKTMEM97 | |
| SCHEMBL29661369 | 0.83 | SUV39H2 (0.45) | EGFRALKPLK1STAT3 | |
| SCHEMBL310055 | 0.83 | SUV39H2 (0.45) | EGFRALKPLK1STAT3 | |
| Hydrochloric Acid SCHEMBL29367159 | 0.82 | SUV39H2 (0.44) | EGFRALKPLK1STAT3 | |
| SCHEMBL28751702 | 0.80 | MAPT (0.55) | IP6K1 | |
| SCHEMBL28542734 | 0.80 | IP6K1 (0.55) | IP6K1L3MBTL1 | |
| SCHEMBL28603306 | 0.80 | ALK (0.45) | LGMNL3MBTL3EGFRALKSTAT3 | |
| SCHEMBL1783282 | 0.80 | MAPT (0.45) | LGMNEGFRALKTMEM97SIGMAR1 | |
| SCHEMBL1912008 | 0.80 | ALK (0.43) | LGMNEGFRALK | |
| SCHEMBL28537166 | 0.79 | L3MBTL3 (0.36) | L3MBTL3EGFRALKTMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313207-B | Cyano-substituted pyridine and cyano-substituted pyrimidine compounds, and preparation methods and applications thereof | 北京赛特明强医药科技有限公司 | 2023-02-14 | — | — | CN | disclosed |
| CN-113087671-B | Cyano-substituted pyridine and cyano-substituted pyrimidine compounds, and preparation methods and applications thereof | 北京赛特明强医药科技有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-113087671-A | Cyano-substituted pyridine and cyano-substituted pyrimidine compounds, and preparation methods and applications thereof | 北京赛特明强医药科技有限公司 | 2021-07-09 | — | — | CN | disclosed |
| CN-112313207-A | Cyano-substituted pyridine and cyano-substituted pyrimidine compounds, and preparation methods and applications thereof | 北京赛特明强医药科技有限公司 | 2021-02-02 | — | — | CN | disclosed |