Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.36 |
| ▸ | PLK1 | P53350 | 5/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | SETD2 | Q9BYW2 | 4/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28532037 | 0.84 | ALDH1A1 (0.36) | — | |
| SCHEMBL28526641 | 0.82 | KDM4E (0.36) | — | |
| SCHEMBL28537165 | 0.80 | L3MBTL3 (0.36) | L3MBTL3IKBKBEGFRL3MBTL1 | |
| SCHEMBL28539777 | 0.79 | MAPT (0.40) | TMEM97SIGMAR1 | |
| SCHEMBL28535183 | 0.79 | LGMN (0.43) | L3MBTL3PLK1EGFRSTAT3ALK | |
| SCHEMBL28953572 | 0.77 | L3MBTL3 (0.34) | L3MBTL3IKBKBEGFRALKDDR1 | |
| SCHEMBL28611481 | 0.72 | L3MBTL3 (0.42) | L3MBTL3PLK1IKBKBEGFRALK | |
| SCHEMBL28388910 | 0.71 | NR1H4 (0.36) | — | |
| SCHEMBL28532473 | 0.70 | L3MBTL3 (0.38) | L3MBTL3IKBKBEGFRALKSIGMAR1 | |
| SCHEMBL23328575 | 0.69 | SUV39H2 (0.43) | PLK1EGFRSTAT3ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313207-B | Cyano-substituted pyridine and cyano-substituted pyrimidine compounds, and preparation methods and applications thereof | 北京赛特明强医药科技有限公司 | 2023-02-14 | — | — | CN | disclosed |
| CN-113087671-B | Cyano-substituted pyridine and cyano-substituted pyrimidine compounds, and preparation methods and applications thereof | 北京赛特明强医药科技有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-113087671-A | Cyano-substituted pyridine and cyano-substituted pyrimidine compounds, and preparation methods and applications thereof | 北京赛特明强医药科技有限公司 | 2021-07-09 | — | — | CN | disclosed |
| CN-112313207-A | Cyano-substituted pyridine and cyano-substituted pyrimidine compounds, and preparation methods and applications thereof | 北京赛特明强医药科技有限公司 | 2021-02-02 | — | — | CN | disclosed |