Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 4/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28532578 | 0.91 | KIF11 (0.37) | HSD11B1KIF11CYP3A4HTR2CP2RY14 | |
| SCHEMBL28535402 | 0.90 | HSD11B1 (0.38) | HSD11B1KIF11CYP3A4HTR2CELANE | |
| SCHEMBL23632253 | 0.89 | HSD11B1 (0.40) | HSD11B1KIF11CYP3A4HTR2CP2RY14 | |
| SCHEMBL28537768 | 0.89 | HSD11B1 (0.38) | HSD11B1KIF11CYP3A4HTR2CP2RY14 | |
| SCHEMBL28540005 | 0.87 | KIF11 (0.41) | HSD11B1KIF11CYP3A4HTR2CP2RY14 | |
| SCHEMBL21616597 | 0.84 | SRD5A2 (0.37) | P2RY14 | |
| SCHEMBL21616615 | 0.84 | HSD11B1 (0.42) | HSD11B1KIF11CYP3A4HTR2CP2RY14 | |
| SCHEMBL23632362 | 0.84 | HSD11B1 (0.42) | HSD11B1KIF11CYP3A4HTR2CP2RY14 | |
| SCHEMBL28539964 | 0.81 | HSD11B1 (0.42) | HSD11B1KIF11CYP3A4HTR2CP2RY14 | |
| SCHEMBL28537013 | 0.81 | ELANE (0.36) | HSD11B1KIF11CYP3A4P2RY14ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513021-B | ROR gamma antagonist and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-112513021-A | ROR gamma antagonist and application thereof in medicine | 广东东阳光药业有限公司 | 2021-03-16 | — | — | CN | disclosed |