Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18613698 | 0.95 | MAPT (0.36) | ALDH1A1SMN1; SMN2KMT2ACYP1A2CYP2C9 | |
| SCHEMBL25653711 | 0.94 | TOP2A (0.39) | SMN1; SMN2KMT2AALOX15LMNAAKR1C3 | |
| SCHEMBL5605689 | 0.94 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2KMT2ACYP1A2CYP2C9 | |
| SCHEMBL24878406 | 0.92 | MAPT (0.33) | ALDH1A1SMN1; SMN2KMT2ACYP1A2CYP2C9 | |
| SCHEMBL19608800 | 0.91 | ALOX15 (0.36) | ALDH1A1SMN1; SMN2KMT2ACYP1A2CYP2C9 | |
| SCHEMBL18613700 | 0.91 | TSHR (0.36) | ALDH1A1SMN1; SMN2KMT2ACYP1A2CYP2C9 | |
| SCHEMBL22125759 | 0.88 | ALOX5 (0.36) | ALDH1A1SMN1; SMN2KMT2ACYP1A2CYP2C9 | |
| SCHEMBL15283358 | 0.85 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2KMT2ACYP2C9MAPT | |
| SCHEMBL29627072 | 0.85 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL18114100 | 0.84 | ELANE (0.40) | ALDH1A1CYP2C9MAPTLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164657-A | Prodrugs of directed lymphatics | 莫纳什大学 | 2023-12-05 | — | — | CN | disclosed |
| CN-117088931-A | Prodrugs of directed lymphatics | 莫纳什大学 | 2023-11-21 | — | — | CN | disclosed |
| CN-106715456-B | Prodrugs of directed lymphatics | 莫纳什大学 | 2023-08-29 | — | — | CN | disclosed |
| CN-112430250-A | Lymphatic prodrugs | 莫纳什大学 | 2021-03-02 | — | — | CN | disclosed |