Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18613700 | 0.96 | TSHR (0.36) | MAPTHSD17B10ALDH1A1TSHRHPGD | |
| SCHEMBL28535446 | 0.95 | ALDH1A1 (0.35) | MAPTHSD17B10ALDH1A1TSHRHPGD | |
| SCHEMBL24878406 | 0.95 | MAPT (0.33) | MAPTHSD17B10ALDH1A1TSHRHPGD | |
| SCHEMBL19608800 | 0.93 | ALOX15 (0.36) | MAPTHSD17B10ALDH1A1TSHRHPGD | |
| SCHEMBL5605689 | 0.91 | ALDH1A1 (0.35) | MAPTHSD17B10ALDH1A1TSHRHPGD | |
| SCHEMBL25653711 | 0.89 | TOP2A (0.39) | LMNAALOX15KMT2ASMN1; SMN2 | |
| SCHEMBL15283358 | 0.87 | ALDH1A1 (0.37) | MAPTHSD17B10ALDH1A1HPGDLMNA | |
| SCHEMBL26264818 | 0.87 | AR (0.33) | — | |
| SCHEMBL18114100 | 0.86 | ELANE (0.40) | MAPTALDH1A1LMNANPSR1CYP2C9 | |
| SCHEMBL17464403 | 0.85 | ALDH1A1 (0.52) | MAPTHSD17B10ALDH1A1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118063537-A | Prodrugs of directed lymphatics | 莫纳什大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-108137482-B | Prodrugs of directed lymphatics | 莫纳什大学 | 2024-03-15 | — | — | CN | disclosed |
| US-20240050573-A1 | LYMPH DIRECTING PRODRUGS | MONASH UNIVERSITY (AU) | 2024-02-15 | — | — | US | disclosed |
| US-11738087-B2 | Lymph directing prodrugs | MONASH UNIVERSITY (AU) | 2023-08-29 | — | — | US | disclosed |
| CN-114031658-A | Lymphatic prodrugs | 莫纳什大学 | 2022-02-11 | — | — | CN | disclosed |
| US-20180243425-A1 | LYMPH DIRECTING PRODRUGS | MONASH UNIVERSITY (AU) | 2018-08-30 | — | — | US | disclosed |
| EP-3347340-A1 | LYMPH DIRECTING PRODRUGS | Monash University (AU) | 2018-07-18 | — | — | EP | disclosed |
| WO-2017041139-A1 | LYMPH DIRECTING PRODRUGS | MONASH UNIVERSITY (AU) | 2017-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240050573-A1 | LYMPH DIRECTING PRODRUGS | LTA, ABCB11, LYN | MAPT 2633/4885HSD17B10 1871/4885ALDH1A1 1056/4885 |
| US-20180243425-A1 | LYMPH DIRECTING PRODRUGS | MLNR, ABCB11, MLN | MAPT 1774/4885HSD17B10 2244/4885ALDH1A1 1385/4885 |
| US-11738087-B2 | Lymph directing prodrugs | MLNR, ABCB11, MLN | MAPT 1774/4885HSD17B10 2244/4885ALDH1A1 1385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.