Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEH1 | O60930 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5778710 | 0.85 | SMN1; SMN2 (0.52) | ALDH1A1KDM4ETSHRMAPTNPSR1 | |
| SCHEMBL27364245 | 0.84 | LMNA (0.46) | ALDH1A1HPGDMAPTCYP2C9CYP2C19 | |
| SCHEMBL4017043 | 0.84 | HCAR2 (0.45) | ALDH1A1HPGDTSHRCYP2C9 | |
| SCHEMBL27866307 | 0.81 | PLA2G2A (0.46) | ALDH1A1HPGDCYP2C9 | |
| SCHEMBL718165 | 0.77 | TSHR (0.40) | ALDH1A1KDM4ETSHRMAPTGAA | |
| SCHEMBL29047812 | 0.76 | PARP1 (0.37) | ALDH1A1KDM4EHPGDTSHRMAPT | |
| SCHEMBL4500023 | 0.76 | L3MBTL1 (0.60) | ALDH1A1KDM4EHPGDTSHRMAPT | |
| SCHEMBL369544 | 0.76 | NPC1 (0.39) | ALDH1A1KDM4ETSHRMAPTCA1 | |
| SCHEMBL4532434 | 0.75 | ALDH1A1 (0.52) | RNASEH1ALDH1A1KDM4ETSHRMAPT | |
| SCHEMBL31624309 | 0.75 | TSHR (0.36) | ALDH1A1KDM4ETSHRMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112566636-A | Compound and use thereof | 优曼尼蒂治疗公司 | 2021-03-26 | — | — | CN | disclosed |