Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.65 |
| ▸ | CA1 | P00915 | 4/20 | 0.65 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | ESRRG | P62508 | 3/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.56 |
| ▸ | ESRRB | O95718 | 1/20 | 0.56 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.53 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | KDM4A | O75164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15019672 | 1.00 | CA2 (0.65) | CA2CA1CA12CA9ESRRG | |
| SCHEMBL4054764 | 0.90 | CA2 (0.77) | CA2CA1CA12CA9PTPN1 | |
| SCHEMBL4054766 | 0.90 | CA2 (0.77) | CA2CA1CA12CA9PTPN1 | |
| SCHEMBL8671997 | 0.90 | CA2 (0.77) | CA2CA1CA12CA9PTPN1 | |
| SCHEMBL15037217 | 0.90 | CA2 (0.55) | CA2CA1CA12CA9ESRRG | |
| SCHEMBL8165005 | 0.89 | PTPN1 (0.67) | CA2CA1CA12CA9PTPN1 | |
| SCHEMBL8165003 | 0.89 | PTPN1 (0.67) | CA2CA1CA12CA9PTPN1 | |
| SCHEMBL6744963 | 0.88 | ACE (0.62) | CA2CA1PTPN1ALDH1A1MAPT | |
| SCHEMBL5926142 | 0.88 | ACE (0.62) | CA2CA1PTPN1ALDH1A1MAPT | |
| SCHEMBL15037181 | 0.88 | CA1 (0.53) | CA2CA1CA12CA9ESRRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074820-B | GLP-1 receptor modulators | 赛尔基因第二国际有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-112457301-A | Novel GLP-1 receptor modulators | 赛尔基因第二国际有限公司 | 2021-03-09 | — | — | CN | disclosed |