Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | ESRRG | P62508 | 3/20 | 0.47 |
| ▸ | ESRRB | O95718 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15019672 | 0.90 | CA2 (0.65) | CA2CA1CA12CA9PTPN1 | |
| SCHEMBL28535866 | 0.90 | CA2 (0.65) | CA2CA1CA12CA9PTPN1 | |
| SCHEMBL15037181 | 0.85 | CA1 (0.53) | CA2CA1CA12CA9PTPN1 | |
| SCHEMBL6744963 | 0.84 | ACE (0.62) | CA2CA1PTPN1MMEACE | |
| SCHEMBL5926142 | 0.84 | ACE (0.62) | CA2CA1PTPN1MMEACE | |
| SCHEMBL15096638 | 0.83 | ITGB3 (0.55) | — | |
| SCHEMBL15037369 | 0.83 | S1PR4 (0.51) | CA2CA1CA12CA9KDM4E | |
| SCHEMBL22448929 | 0.83 | S1PR4 (0.51) | CA2CA1CA12CA9KDM4E | |
| SCHEMBL22448977 | 0.81 | KIFC1 (0.43) | MMEACEACE2KDM4EKDM4A | |
| SCHEMBL15037339 | 0.81 | KIFC1 (0.43) | MMEACEACE2KDM4EKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013090454-A2 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS, INC. (US) | 2013-06-20 | — | — | WO | disclosed |