SCHEMBL28535946

SCHEMBL28535946

O=C(O)c1cc2ccsc2n1S(=O)(=O)C1CC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.39
RCOR1 Q9UKL0 1/20 0.39
L3MBTL1 Q9Y468 3/20 0.34
LMNA P02545 2/20 0.34
TSHR P16473 4/20 0.34
MAPT P10636 1/20 0.34
AKR1C3 P42330 1/20 0.33
CCR2 P41597 1/20 0.33
DAO P14920 2/20 0.33
TP53 P04637 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ACLY P53396 1/20 0.31
MCL1 Q07820 2/20 0.31
POLB P06746 2/20 0.31
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
FABP3 P05413 1/20 0.30
FABP2 P12104 1/20 0.30
FABP4 P15090 1/20 0.30
FABP5 Q01469 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23159501 0.81 NOD2 (0.43) L3MBTL1LMNATSHRMAPTTP53
SCHEMBL23159500 0.77 TSHR (0.30) L3MBTL1LMNATSHR
SCHEMBL23159535 0.75 CYP2A6 (0.32)
SCHEMBL28538325 0.71 NOTUM (0.41) KDM1ARCOR1L3MBTL1LMNATSHR
SCHEMBL17554479 0.70 KDM1A (0.64) KDM1ARCOR1L3MBTL1LMNATSHR
SCHEMBL5885340 0.70 KDM1A (0.46) KDM1ARCOR1L3MBTL1LMNATSHR
SCHEMBL28833744 0.69 FEN1 (0.44) KDM1ARCOR1L3MBTL1LMNATSHR
SCHEMBL28542193 0.69 KDM1A (0.37) KDM1ARCOR1L3MBTL1LMNATSHR
SCHEMBL2331226 0.65 KDM1A (0.47) KDM1ARCOR1L3MBTL1LMNATSHR
SCHEMBL28833751 0.64 L3MBTL1 (0.43) KDM1ARCOR1L3MBTL1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112574230-B Peptidyl arginine deiminase inhibitors and uses thereof 药捷安康(南京)科技股份有限公司 2022-10-28 CN disclosed
CN-112574230-A Peptidyl arginine deiminase inhibitors and uses thereof 南京药捷安康生物科技有限公司 2021-03-30 CN disclosed