Sugi Predict

Sugi Predict / Compounds / SCHEMBL355627

SCHEMBL355627

SCHEMBL355627

O=C(O)CCOc1ccc(Cl)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 3/20 0.67
▸ MMP2 P08253 1/20 0.57
▸ MCL1 Q07820 1/20 0.56
▸ KMT2A Q03164 4/20 0.51
▸ MEN1 O00255 3/20 0.51
▸ HPGD P15428 2/20 0.51
▸ ALDH1A1 P00352 2/20 0.51
▸ RAB9A P51151 1/20 0.51
▸ HTT P42858 1/20 0.51
▸ NPSR1 Q6W5P4 1/20 0.51
▸ PPARG P37231 1/20 0.51
▸ PPARA Q07869 1/20 0.51
▸ FFAR1 O14842 2/20 0.50
▸ TSHR P16473 1/20 0.50
▸ NR4A2 P43354 1/20 0.50
▸ LMNA P02545 1/20 0.50
▸ USP2 O75604 1/20 0.49
▸ TAAR1 Q96RJ0 1/20 0.49
▸ CYP1A2 P05177 1/20 0.49
▸ CYP3A4 P08684 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8582394 0.94 L3MBTL1 (0.61) L3MBTL1MMP2MCL1FFAR1
SCHEMBL21991829 0.91 PPARA (0.62) L3MBTL1MMP2MCL1HPGDALDH1A1
SCHEMBL120716 0.90 KMT2A (0.58) L3MBTL1KMT2AMEN1HPGDALDH1A1
SCHEMBL21991528 0.90 NR4A2 (0.67) L3MBTL1FFAR1NR4A2
SCHEMBL28536384 0.89 PPARA (0.63) L3MBTL1KMT2AMEN1HPGDALDH1A1
SCHEMBL24805947 0.88 L3MBTL1 (0.54) L3MBTL1MMP2MCL1KMT2AMEN1
SCHEMBL28555169 0.87 PPARA (0.61) L3MBTL1KMT2AMEN1HPGDALDH1A1
SCHEMBL8922627 0.87 PPARA (0.61) L3MBTL1KMT2AMEN1HPGDALDH1A1
SCHEMBL6545281 0.87 PPARA (0.61) L3MBTL1KMT2AMEN1HPGDALDH1A1
SCHEMBL8921579 0.87 PPARA (0.61) L3MBTL1KMT2AMEN1HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8765639-B2 Alkoxylated asymmetric alkylamine surfactants as adjuvants AKZO NOBEL N.V. (NL) 2014-07-01 — — US claimed
CN-101686670-B Alkoxylated asymmetric alkylamine surfactants as adjuvants AKZO NOBEL NV 2013-11-06 — — CN claimed
EP-2161992-B1 ALKOXYLATED ASYMMETRIC ALKYLAMINE SURFACTANTS AS ADJUVANTS AKZO NOBEL NV (NL) 2010-11-17 — — EP claimed
US-20100204047-A1 Alkoxylated asymmetric alkylamine surfactants as adjuvants AKZO NOBEL N.V. (NL) 2010-08-12 — — US claimed
CN-101686670-A Alkoxylated asymmetric alkylamine surfactants as adjuvants AKZO NOBEL NV 2010-03-31 — — CN claimed
EP-2161992-A1 ALKOXYLATED ASYMMETRIC ALKYLAMINE SURFACTANTS AS ADJUVANTS Akzo Nobel N.V. (NL) 2010-03-17 — — EP claimed
WO-2009004044-A1 ALKOXYLATED ASYMMETRIC ALKYLAMINE SURFACTANTS AS ADJUVANTS AKZO NOBEL N.V. (NL) 2009-01-08 — — WO claimed
CN-118266473-A Pest control agent composition for agricultural and horticultural applications and method for using the same 日本农药株式会社 2024-07-02 — — CN disclosed
US-20220409566-A1 CCL5 Inhibitors LAPKO INC, dba AFECTA PHARMACEUTICALS 2022-12-29 — — US disclosed
CN-111592998-B Degrading strain of phenoxyacetic acid herbicide methoxone and microbial inoculum produced by degrading strain 南京农业大学 2022-09-23 — — CN disclosed
US-20220142961-A1 CCL5 Inhibitors LAPKO INC, dba AFECTA PHARMACEUTICALS 2022-05-12 — — US disclosed
US-11318111-B2 CCL5 inhibitors LAPKO INC (US) 2022-05-03 — — US disclosed
US-20210196665-A1 CCL5 Inhibitors AFECTA PHARMACEUTICALS, INC. (US) 2021-07-01 — — US disclosed
EP-0207690-A1 N-Substituted glutamic acid derivative and process for production and use thereof SUNTORY LIMITED (JP) 1987-01-07 — — EP disclosed
US-4632933-A Sulfur-containing imidazole derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1986-12-30 — — US disclosed
US-4598087-A DIURETICS; ANALGESICS, PSYCHOTHERAPEUTICS WARNER-LAMBERT COMPANY (US) 1986-07-01 — — US disclosed
EP-0068041-B1 FLOWABLE HERBICIDE AND PESTICIDE COMPOSITIONS AND THEIR USE J.T. Baker Chemical Co. (US) 1985-08-21 — — EP disclosed
EP-0146297-A1 Substituted trans-1,2-diaminocyclohexyl amide compounds WARNER-LAMBERT COMPANY (US) 1985-06-26 — — EP disclosed
EP-0120239-A2 Sulfur-containing imidazole derivatives MERCK PATENT GmbH (DE) 1984-10-03 — — EP disclosed
US-4008324-A Phenoxyalkylcarboxylic acid salt of 1-cinnamyl-4-diphenylmethyl piperazine, method of preparation and antihypercholesteremic LUDWIG MERCKLE KG (DT) 1977-02-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220142961-A1 CCL5 Inhibitors CCL5, CCL11, CCR5 L3MBTL1 1170/4885MMP2 885/4885MCL1 767/4885
US-20100204047-A1 Alkoxylated asymmetric alkylamine surfactants as adjuvants ALK, CHRM2, CHRM1 L3MBTL1 1578/4885MMP2 3442/4885MCL1 2213/4885
US-20210196665-A1 CCL5 Inhibitors CCL5, CCL11, CCR5 L3MBTL1 1170/4885MMP2 885/4885MCL1 767/4885
US-11318111-B2 CCL5 inhibitors CCL5, CCL11, CCR5 L3MBTL1 1170/4885MMP2 885/4885MCL1 767/4885
US-20220409566-A1 CCL5 Inhibitors CCL5, CCL11, CCR5 L3MBTL1 1170/4885MMP2 885/4885MCL1 767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.