SCHEMBL28536859

SCHEMBL28536859

CC(C(=O)CBr)N1C(=O)c2ccccc2C1=O

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.58
ALDH1A1 P00352 3/20 0.56
HTT P42858 2/20 0.56
NPC1 O15118 1/20 0.55
KMT2A Q03164 2/20 0.54
GAA P10253 2/20 0.54
TSHR P16473 2/20 0.52
NPSR1 Q6W5P4 2/20 0.52
TP53 P04637 1/20 0.52
MAPK1 P28482 1/20 0.52
USP2 O75604 1/20 0.51
MAPT P10636 2/20 0.49
POLB P06746 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2821892 0.84 LMNA (0.60) LMNAALDH1A1HTTNPC1KMT2A
SCHEMBL27883377 0.83 ALDH1A1 (0.45) LMNAALDH1A1HTTNPC1KMT2A
SCHEMBL3717856 0.81 ALDH1A1 (0.51) LMNAALDH1A1HTTNPC1KMT2A
SCHEMBL10577708 0.80 LMNA (0.68) LMNAALDH1A1HTTNPC1KMT2A
SCHEMBL11453215 0.79 LMNA (0.54) LMNAALDH1A1HTTKMT2AGAA
SCHEMBL8977751 0.78 LMNA (0.66) LMNAALDH1A1HTTNPC1KMT2A
SCHEMBL125972 0.78 LMNA (0.71) LMNAALDH1A1HTTNPC1KMT2A
SCHEMBL7399848 0.78 LMNA (0.71) LMNAALDH1A1HTTNPC1KMT2A
SCHEMBL478339 0.78 LMNA (0.71) LMNAALDH1A1HTTNPC1KMT2A
SCHEMBL29472125 0.78 LMNA (0.71) LMNAALDH1A1HTTNPC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105819618-A Device for treating suspended matter in sewage through flocculation aeration composite method and removing method thereof 江苏建筑职业技术学院 2016-08-03 CN claimed
CN-112341373-B Preparation method of ftibamzone 山东嘉成医药科技有限公司 2022-04-08 CN disclosed
CN-112341373-A Preparation method of ftibamzone 山东嘉成医药科技有限公司 2021-02-09 CN disclosed
CN-105819618-A Device for treating suspended matter in sewage through flocculation aeration composite method and removing method thereof 江苏建筑职业技术学院 2016-08-03 CN disclosed