Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 6/20 | 0.36 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2474184 | 0.86 | MAOA (0.52) | TAAR1MAOAMAOBIDO1KDM1A | |
| SCHEMBL4052580 | 0.80 | OPRL1 (0.44) | TAAR1MAOAMAOBIDO1OPRL1 | |
| Formic Acid SCHEMBL5135412 | 0.77 | MAOB (0.43) | TAAR1MAOAMAOBIDO1ALDH1A1 | |
| SCHEMBL8267928 | 0.75 | DPP4 (0.44) | TAAR1MAOAMAOBIDO1KDM1A | |
| SCHEMBL7453823 | 0.74 | ALDH1A1 (0.53) | ALDH1A1 | |
| SCHEMBL28544407 | 0.72 | MAOB (0.46) | TAAR1MAOAMAOBIDO1KDM1A | |
| SCHEMBL9957112 | 0.72 | TAAR1 (0.36) | TAAR1MAOAMAOBIDO1KDM1A | |
| SCHEMBL3885819 | 0.71 | GAA (0.47) | ALDH1A1 | |
| SCHEMBL9957480 | 0.71 | GRIN2B (0.40) | TAAR1IDO1 | |
| SCHEMBL12821714 | 0.70 | MAOB (0.56) | TAAR1MAOAMAOBIDO1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108135175-B | Bicyclic compounds and their use for inhibition of SUV39H2 | 肿瘤疗法科学股份有限公司 | 2021-04-06 | — | — | CN | disclosed |