Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.53 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 9/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5909497 | 0.91 | CYP3A4 (0.67) | ALDH1A1ALDH3A1ALDH1A3CYP3A4TSHR | |
| SCHEMBL11430133 | 0.83 | ALDH1A1 (0.50) | ALDH1A1ALDH3A1ALDH1A3CYP3A4TSHR | |
| SCHEMBL18600545 | 0.82 | CNR2 (0.47) | ALDH1A1CYP3A4TSHRMAPK1KDM4E | |
| SCHEMBL3163386 | 0.81 | CYP3A4 (0.54) | ALDH1A1CYP3A4TSHRL3MBTL1TDP1 | |
| SCHEMBL1456966 | 0.80 | P2RY6 (0.50) | ALDH1A1ALDH3A1ALDH1A3CYP3A4TSHR | |
| SCHEMBL11099185 | 0.78 | ALDH1A1 (0.45) | ALDH1A1ALDH3A1ALDH1A3CYP3A4TSHR | |
| Butane SCHEMBL16872374 | 0.78 | CYP3A4 (0.62) | ALDH1A1CYP3A4TSHRTDP1MAPK1 | |
| SCHEMBL9232459 | 0.78 | ALDH1A1 (0.49) | ALDH1A1ALDH3A1ALDH1A3CYP3A4TSHR | |
| SCHEMBL4902297 | 0.77 | CYP3A4 (0.47) | ALDH1A1CYP3A4TSHRTDP1MAPK1 | |
| SCHEMBL163992 | 0.77 | TSHR (0.58) | ALDH1A1CYP3A4TSHRL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7807669-B2 | Biaromatic compounds which activate PPARγ type receptors and cosmetic/pharmaceutical compositions comprised thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-10-05 | — | — | US | disclosed |
| EP-1575911-B1 | BIAROMATIC COMPOUNDS WHICH ACTIVATE PPAR-GAMMA TYPE RECEPTORS AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2010-01-13 | — | — | EP | disclosed |
| US-20090062340-A1 | NOVEL BIAROMATIC COMPOUNDS WHICH ACTIVATE PPARY TYPE RECEPTORS AND COSMETIC/PHARMACEUTICAL COMPOSITIONS COMPRISED THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2009-03-05 | — | — | US | disclosed |
| US-7470698-B2 | Adenosine A3 receptor modulators | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) | 2008-12-30 | — | — | US | disclosed |
| US-7452878-B2 | Biaromatic compounds which activate PPARγ type receptors and cosmetic/pharmaceutical compositions comprised thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2008-11-18 | — | — | US | disclosed |
| US-20070249641-A1 | ADENOSINE A3 RECEPTOR MODULATORS | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. | 2007-10-25 | — | — | US | disclosed |
| US-7271171-B2 | Adenosine A3 receptor modulators | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) | 2007-09-18 | — | — | US | disclosed |
| US-20060040959-A1 | Adenosine A3 receptor modulators | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. | 2006-02-23 | — | — | US | disclosed |
| US-20050256116-A1 | Novel biaromatic compounds which activate PPARy type receptors and cosmetic/pharmaceutical compositions comprised thereof | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-11-17 | — | — | US | disclosed |
| EP-1575911-A2 | BIAROMATIC COMPOUNDS WHICH ACTIVATE PPAR-GAMMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2005-09-21 | — | — | EP | disclosed |
| WO-1996000928-A1 | CHROMOGENIC LEUCO REDOX-DYE-RELEASING COMPOUNDS FOR PHOTOTHERMOGRAPHIC ELEMENTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-01-11 | — | — | WO | disclosed |
| EP-0689683-A1 | YELLOW AND MAGENTA CHROMOGENIC LEUCO DYES FOR PHOTOTHERMOGRAPHIC ELEMENTS | MINNESOTA MINING & MFG (US) | 1996-01-03 | — | — | EP | disclosed |
| US-5470816-A | Urea developers | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1995-11-28 | — | — | US | disclosed |
| US-5432041-A | Yellow and magenta chromogenic leuco dyes for photothermographic elements | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-07-11 | — | — | US | disclosed |
| EP-0633145-A1 | Thermal recording sheet | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1995-01-11 | — | — | EP | disclosed |
| WO-1994022052-A1 | YELLOW AND MAGENTA CHROMOGENIC LEUCO DYES FOR PHOTOTHERMOGRAPHIC ELEMENTS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-09-29 | — | — | WO | disclosed |
| US-4405623-A | HYPOTENSIVE AGENTS, VASODILATORS | MASAYUKI ISHIKAWA (JP) | 1983-09-20 | — | — | US | disclosed |
| EP-0040793-A1 | Novel quinazoline-dione compounds, process for production thereof and pharmaceutical use thereof | Ishikawa, Masayuki (JP) | 1981-12-02 | — | — | EP | disclosed |
| US-4088766-A | PRODUCTION OF PROSTAGLANDINS IN MAMMALS | THE UPJOHN COMPANY (US) | 1978-05-09 | — | — | US | disclosed |
| US-4001256-A | PROSTAGLANDIN PRODUCTION IN MAMMALS | THE UPJOHN COMPANY (US) | 1977-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062340-A1 | NOVEL BIAROMATIC COMPOUNDS WHICH ACTIVATE PPARY TYPE RECEPTORS AND COSMETIC/PHARMACEUTICAL COMPOSITIONS COMPRISED THEREOF | PPARG, PPARA, PPARD | ALDH1A1 531/4885ALDH3A1 725/4885ALDH1A3 644/4885 |
| US-20060040959-A1 | Adenosine A3 receptor modulators | ADORA3, ADORA2A, ADORA1 | ALDH1A1 549/4885ALDH3A1 503/4885ALDH1A3 295/4885 |
| US-20050256116-A1 | Novel biaromatic compounds which activate PPARy type receptors and cosmetic/pharmaceutical compositions comprised thereof | PPARG, PPARA, PPARD | ALDH1A1 531/4885ALDH3A1 725/4885ALDH1A3 644/4885 |
| US-20070249641-A1 | ADENOSINE A3 RECEPTOR MODULATORS | ADORA3, ADORA2A, ADORA1 | ALDH1A1 549/4885ALDH3A1 503/4885ALDH1A3 295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.